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Literature summary for 3.1.1.56 extracted from
- Purification and characterization of esterases D1 and D2 from human erythrocytes. Evidence that they are monomers (1985), Eur. J. Biochem., 153, 217-222.
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.03 | - |
4-yethylumbelliferyl acetate | pH 5.2, 37°C, isoenzymes Es D1 and Es D2 | Homo sapiens |  |
| 0.067 | - |
4-Methylumbelliferyl butyrate | pH 5.2, 37°C, isoenzymes Es D1 and Es D2 | Homo sapiens | |
| 0.55 | - |
4-nitrophenyl butyrate | pH 5.2, 37°C, isoenzyme Es D1n | Homo sapiens | |
| 0.83 | - |
4-nitrophenyl butyrate | pH 5.2, 37°C, isoenzyme Es D2 | Homo sapiens | |
| 0.9 | - |
4-nitrophenyl acetate | pH 5.2, 37°C, isoenzymes Es D1 and Es D2 | Homo sapiens | |
| 2.5 | - |
1-naphthyl acetate | pH 5.2, 37°C, isoenzyme Es D1 | Homo sapiens | |
| 2.9 | - |
2-naphthyl acetate | pH 5.2, 37°C, isoenzyme Es D2 | Homo sapiens | |
| 3.1 | - |
1-naphthyl acetate | pH 5.2, 37°C, isoenzyme Es D2 | Homo sapiens | |
| 4 | - |
2-naphthyl acetate | pH 5.2, 37°C, isoenzyme Es D1 | Homo sapiens | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 27000 | - |
isoenzyme Es D1 and Es D2, gel filtration | Homo sapiens |
| 34000 | - |
1 * 34000, isoenzyme Es D1 and Es D2, SDS-PAGE | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 4-methylumbelliferyl acetate + H2O | Homo sapiens | - |
4-methylumbelliferone + acetate | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Posttranslational Modification
| Posttranslational Modification | Comment | Organism |
|---|---|---|
| additional information | isoenzymes contain very little if any carbohydrate | Homo sapiens |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| isoenzyme Es D1 and Es D2 | Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
- |
Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 1-naphthyl acetate + H2O | - |
Homo sapiens | 1-naphthol + acetate | - |
? | |
| 2-naphthyl acetate + H2O | - |
Homo sapiens | 2-naphthol + acetate | - |
? | |
| 4-methylumbelliferyl acetate + H2O | - |
Homo sapiens | 4-methylumbelliferone + acetate | - |
? | |
| 4-methylumbelliferyl butyrate + H2O | - |
Homo sapiens | 4-methylumbelliferone + butyrate | - |
? | |
| 4-nitrophenyl acetate + H2O | - |
Homo sapiens | 4-nitrophenol + acetate | - |
? | |
| 4-nitrophenyl butyrate + H2O | - |
Homo sapiens | 4-nitrophenol + butyrate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| monomer | 1 * 34000, isoenzyme Es D1 and Es D2, SDS-PAGE | Homo sapiens |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8 | - |
- |
Homo sapiens |
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